منابع مشابه
Cell-Size Control.
Cells of a given type maintain a characteristic cell size to function efficiently in their ecological or organismal context. They achieve this through the regulation of growth rates or by actively sensing size and coupling this signal to cell division. We focus this review on potential size-sensing mechanisms, including geometric, external cue, and titration mechanisms. Mechanisms that titrate ...
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Cells usually grow to a proper size before they divide. To ensure an optimal size for cell survival and function, it is crucial that cells develop efficient and sensitive mechanisms for cell-size control. in 2009, 2 independent studies proposed that the DyRK-family kinase Pom1 could serve as a cell-length sensor to negatively regulate mitotic entry through sAD-like kinase Cdr2 in fission yeast....
متن کاملSize sensors in bacteria, cell cycle control, and size control
Bacteria proliferate by repetitive cycles of cellular growth and division. The progression into the cell cycle is admitted to be under the control of cell size. However, the molecular basis of this regulation is still unclear. Here I will discuss which mechanisms could allow coupling growth and division by sensing size and transmitting this information to the division machinery. Size sensors co...
متن کاملCell Size Control in Yeast
Cell size is an important adaptive trait that influences nearly all aspects of cellular physiology. Despite extensive characterization of the cell-cycle regulatory network, the molecular mechanisms coupling cell growth to division, and thereby controlling cell size, have remained elusive. Recent work in yeast has reinvigorated the size control field and suggested provocative mechanisms for the ...
متن کاملCell Growth: Control of Cell Size
SYNAPTIC PLASTICITY—THE DYNAMIC MODIFICATION of functional synaptic strength between neurons of the central nervous system—is generally believed to be a physical mechanism underlying learning and memory.An individual neuron in the mammalian CNS may contain up to 10,000 synaptic connections. Furthermore, small groups of synapses can be independently regulated: Synaptic enhancement induced at one...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2016
ISSN: 1538-4101,1551-4005
DOI: 10.1080/15384101.2016.1172471